Meiotic nodules are the sites of double-stranded DNA break repair. Rpa is a single-stranded DNA-binding protein and Rad51 is a protein that assists in the repair of DNA double strand breaks. The ...
Meiotic recombination is initiated by the formation of double-strand breaks (DSBs), which are repaired as either crossovers (COs) or noncrossovers (NCOs). In most mammals, PRDM9-mediated H3K4me3 ...