Organoids have revolutionized science and medicine, providing platforms for disease modeling, drug testing, and understanding developmental processes. While not exact replicas of human organs, they ...

Microglia, the brain's immune cells, usually serve as diligent guardians. They eliminate intruders such as microbes and clear away cellular debris—including the plaques typical of Alzheimer's disease.

Microglial activation, driven by a metabolic shift towards aerobic glycolysis, is implicated in neuroinflammation and neurological disorders like depression. THSG ...

Chronic stress has been associated with an increased inflammatory profile in the brain, linking inflammation to the development of stress-related disorders. Although the detailed mechanism connecting ...

Researchers at Northwestern University have identified a specific step inside brain synapses where the toxic Alzheimer’s ...

The study found that elevated levels of the lipid LPA trigger a cascade of neuroinflammatory events that can lead to pain on ...

Scientists have uncovered a microglial switch that transforms these immune cells from plaque-promoting to plaque-protective, offering a new path toward immunomodulatory treatments for Alzheimer’s ...

Inflammatory pathways involving microglia, astrocytes, and cytokine signaling are widely implicated in disorders including Alzheimer’s disease, Parkinson’s disease, ALS, multiple sclerosis, and ...

More than 55 million people worldwide live with dementia, and Alzheimer’s disease accounts for the majority of cases. Despite the recent arrival of anti-amyloid antibodies like lecanemab, no approved ...

During a session at 38, the Congress of the French Society of Rheumatology (SFR 2025) in Paris, France, Nicolas Villain, MD, neurologist at Pitié-Salpêtrière Hospital in Paris, France, reviewed ...

Alzheimer's disease and other dementias impact approximately 55 million people worldwide, including 7.2 million cases in the United States alone. With 10 million new cases globally each year, the ...