The ensemble-function approach provides a quantitative catalytic model for serine proteases and identifies repeatedly evolved catalytic strategies. Credit: Science (2025). DOI: 10.1126/science.ado5068 ...

Although you may never have heard of the cytochrome P450 superfamily of enzymes, these proteins play diverse and critical roles in humans through the metabolic processing of drugs, pesticides, fatty ...

A team has used neutron crystallography to image all of the atoms in a radical intermediate of a copper amine oxidase enzyme. They disclosed previously unknown details, such as precise conformational ...

By reconstructing ancient nitrogen-processing enzymes, scientists are uncovering new clues about how early life survived on a ...

Man prides himself upon his growing mastery over nature, but in the ultimate biochemical analysis nature remains the master of man. With their most sophisticated laboratory glassware and corrosive ...

Macrolides are an important class of antibiotics that includes drugs such as azithromycin and erythromycin, which are widely used to treat a range of infections, including pneumonia and skin ...

Using a series of more than 1,000 X-ray snapshots of the shapeshifting of enzymes in action, researchers at Stanford University have illuminated one of the great mysteries of life – how enzymes are ...