Together, these results reinforce the notion that PCNA and lagging-strand processes undergo functional exhaustion during unperturbed origin activation and become further depleted upon unscheduled ...

During DNA replication, the two new DNA strands are synthesized asymmetrically, with the leading strand synthesized in a continuous fashion and the lagging strand synthesized as a discontinuous series ...

For the first time, scientists have witnessed the very moment DNA begins to unravel, revealing a necessary molecular event for DNA to be the molecule that codes all life. A new study from King ...

An INRS team discovers a new family of enzymes capable of inducing targeted cuts in single-stranded DNA . A few years ago, the advent of technology known as CRISPR was a major breakthrough in the ...

You can always be judged by your scars. This is the idea that sums up what researchers at Spanish National Cancer Research Centre (CNIO) claim is one of the new breakthroughs in basic and biomedical ...